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The growing push for 3D cell culture models is limited by technical challenges in handling, processing and scalability to high-throughput applications. To meet these challenges, use a magnetic 3D bioprinting platform to make routine cell culture and experiments feasible and scalable and gain fine spatial control in the formation of spheroids and more complex structures.

Learn about:

• General technique of magnetic 3D cell culture and magnetic 3D Bioprinting
• Key advantages of 3D cell culture over other techniques
• Broad applications of 3D cell culture
• Applications in immunobiology
• Comparison between magnetic 3D cell culture and in vivo results in collaboration with MD Anderson Cancer Center
• HTS screening results in collaboration with Scripps Research Institute and Cold Spring Harbor

During the course of this 60 minute webinar, attendees will achieve the following program objectives:

1. Identify the most common preanaytical deficiencies cited.

2. Describe how to prepare a pre-inspection readiness checklist.

3. Discuss development of tools to prepare for a successful inspection.

Ethical, scientific and financial concerns lead to an increasing importance of cell based assays and three-dimensional cell cultures in lieu of live-animal experimentation. With respect to these developments, ThinCert™ cell culture inserts with porous PET membranes are significant because they form a two-compartment system to readily mimic a variety of in vivo situations, such as:

1.  Cell migration and invasion,

2.  Interaction and communication of physically separated cell populations (co-culture)

3.  Trans-epithelial transport,

4.  Tissue growth and differentiation at the air-liquid-interface.

This presentation provides detailed insight in the different application fields of ThinCert™ cell culture inserts. Hints for the individual experimental design and the selection of the appropriate insert type are given.