Diabetes mellitus is one of the most common metabolic disorders in the world. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes. To prevent immediate glycolysis in the event of delay between blood collection and measurement in the lab, test tubes should include a citrate/citric acid buffer as well as sodium fluoride (NaF).


  • Stabilisation immediately after collection for 48 hours
  • Based on the in vivo value (almost 100 %)
  • Avoids false negative diagnoses of diabetes patients
  • Stabilisation allows for longer transport and storage times

The unique additive mixture is what makes the difference

The citrate/citric acid buffer ensures a quick stabilisation of the blood sample. The glycolysis is catalysed and suppressed. Therefore, the blood sugar is held constantly at the in vivo value  . Due to the sodium fluoride additive contained in the VACUETTE® FC Mix Tube, inhibition is extended to 48 hours. Additionally, the Na2-EDTA is included as an anticoagulant, which is effective due to complexation of Ca++. 

The almost full inhibition of glycoloysis in the VACUETTE® FC Mix Tube means that diagnosis is a much more reliable process than before. The stabilisation is carried out in whole blood and therefore does not require immediate centrifugation. Unlike in tubes with liquid additives, the finely granulated additive does not cause a dilution effect.

As such, the VACUETTE® FC Mix Tube is the ideal tool for reliably detecting diabetes and taking appropriate measures to combat the condition.

Further information about our VACUETTE® FC Mix Tube can be found in the Download Center.